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MOCOS (N) Antibody, Rabbit Polyclonal
Catalog Number: orb67220
| Catalog Number | orb67220 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to MOCOS.Molybdenum cofactor sulfurase (MOCOS) belongs to the class-V pyridoxal-phosphate-dependentaminotransferase family. It sulfurates the molybdenum cofactor. Sulfation of molybdenum is essentialfor xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenumcofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain isable to reduce N-hydroxylated prodrugs, such as benzamidoxime. Defects in MOCOS are the causeof xanthinuria type 2 (XU2). Patients suffering XU2 cannot metabolize allopurinol into oxypurinol dueto dual deficiency of xanthine dehydrogenase and aldehyde oxidase. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | N-terminal region of human MOCOS |
| Dilution range | WB:1:500-1:1000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 98 |
| UniProt ID | Q96EN8 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-MOCOS antibody,anti-Molybdenum cofactor sulfu Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human HepG2 using MOCOS antibody
