MOCOS (N) Antibody, Rabbit Polyclonal

SKU: orb67220

Description

Rabbit polyclonal to MOCOS.Molybdenum cofactor sulfurase (MOCOS) belongs to the class-V pyridoxal-phosphate-dependentaminotransferase family. It sulfurates the molybdenum cofactor. Sulfation of molybdenum is essentialfor xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenumcofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain isable to reduce N-hydroxylated prodrugs, such as benzamidoxime. Defects in MOCOS are the causeof xanthinuria type 2 (XU2). Patients suffering XU2 cannot metabolize allopurinol into oxypurinol dueto dual deficiency of xanthine dehydrogenase and aldehyde oxidase.

Research Area

Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human MOCOS
• Molecular Weight: 98
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-MOCOS antibody,anti-Molybdenum cofactor sulfurase antibody,anti-MCS antibody,anti-MOS antibody,anti-MoCo sulfurase antibody,anti-hMCS antibody

Quick Database Links

UniProt

Q96EN8