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Catalog Number | orb67214 |
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Category | Antibodies |
Description | Rabbit polyclonal to MMP16.Matrix metalloproteinase-16 (MMP16) is a single-pass type I membrane protein that belongs to thepeptidase M10A family. It is an endopeptidase that degrades various components of the extracellularmatrix, such as collagen type III and fibronectin, while it has no effect on type I, II, IV and V collagen.MMP16 is involved in the matrix remodeling of blood vessels. MMPs play a central role in cellproliferation, migration, differentiation, angiogenesis, apoptosis and host defences. Dysregulatoin ofMMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis andcancer. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | C-terminal region of human MMP16 |
Dilution range | WB:1:500-1:1000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 69.5 |
UniProt ID | P51512 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-MMP16 antibody,anti-Matrix metalloproteinase1 Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using MMP16 antibody