MLKL Antibody

• Catalog Number: orb1731695
• Category: Antibodies
• Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Recombinant protein of human MLKL
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000
• Conjugation: Unconjugated
• MW: Calculated MW: 54 kDa; Observed MW: 54 kDa
• Entrez: 197259
• UniProt ID: Q8NB16
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: MLKL
• Note: For research use only
• Expiration Date: 12 months from date of receipt.