MKRN1 antibody

• Catalog Number: orb67219
• Category: Antibodies
• Description: Rabbit polyclonal to MKRN1.E3 ubiquitin-protein ligase makorin-1 (MKRN1) catalyzes the covalent attachment of ubiquitin moietiesonto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. MKRN1supports cell survival by suppressing p53/TP53 under normal conditions, but stimulates apoptosis byrepressing CDKN1A under stress conditions. MKRN1 acts as a negative regulator of telomerase andhas negative and positive effects on RNA polymerase II-dependent transcription.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: N-terminal region of human MKRN1
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 53
• UniProt ID: Q9UHC7
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-MKRN1 antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from mouse brain using MKRN1 antibody