MCU Rabbit Polyclonal Antibody

SKU: orb317655

Description

MCU Rabbit Polyclonal Antibody

Research Area

CARdiovascular Research, Cell Biology, Mitochondrial Markers

Images & Validation

• Tested Applications: ELISA, ICC, IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, ICC/IF=1:100-500, IF=1:100-500, ELISA=1:5000-10000
• Reactivity: Mouse, Rat
• Predicted Reactivity: Bovine, Canine, Equine, Human, Porcine, Rabbit, Sheep

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from human MCU (251-351//351aa)
• Target: MCU
• Molecular Weight: 42 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: Preservative: 0.02% Proclin300, Constituents: 1% rAlbumin, 0.01M PBS, pH 7.4.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

C10orf42; CCDC109A; HsMCU; 2010012O16Rik; D130073L02Rik; Gm64; MCU_HUMAN; MCU; Coiled-coil domain-containing protein 109A; MCU_MOUSE; mitochondrial calcium uniporter; coiled-coil domain containing 109A

Quick Database Links

Gene Symbol

MCU

UniProt

Q8NE86

Ziqing Yu, Ruizhen Chen, Minghui Li, Yong Yu, Yixiu Liang, Fei Han, Shengmei Qin, Xueying Chen, Yangang Su, Junbo Ge Mitochondrial calcium uniporter inhibition provides cardioprotection in pressure overload-induced heart failure through autophagy enhancement International Journal of Cardiology, 271, 161 (2018)

PubMed: 29803339

Applications

IHC

Reactivity

Mouse

Ziqing Yu, Xue Gong, Yong Yu, Minghui Li, Yixiu Liang, Shengmei Qin, Zibire Fulati, Nianwei Zhou, Xianhong Shu, Zhenning Nie, Shimo Dai, Xueying Chen, Jingfeng Wang, Ruizhen Chen, Yangang Su, Junbo Ge The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down‐regulation and mitochondrial dynamics alteration Journal of Cellular and Molecular Medicine, 23, 3833 (2019)

PubMed: 30938090

Applications

IF, WB

Reactivity

Canine

Yu, Ziqing et al. The mechanical effects of CRT promoting autophagy via mitochondrial calcium uniporter down-regulation and mitochondrial dynamics alteration J. Cell. Mol. Med., (2019)

PubMed: 30938090

Applications

IF, WB

Reactivity

Canine