MART-1/Melan-A antibody

• Catalog Number: orb29662
• Category: Antibodies
• Description: Rabbit polyclonal antibody to p16INK4a is a negative regulator of CDK4, CDK6 kinase activity and cell cycle progression. It regulates the cell cycle by inhibiting cyclin/CDK complex formation and the phosphorylation of the retinoblastoma protein (pRb).It regulates the cell cycle, and mutations in p16 that increases the risk of developing a variety of cancers, and notably melanoma.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Clone Number: RB19079
• Tested applications: FC, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: Synthetic Peptide
• Dilution range: WB: 1:1000, FACS: 1:10-50
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• MW: 13157
• Target: MLANA
• UniProt ID: Q16655
• NCBI: NP_005502.1
• Alternative names: Anti-RB19079 antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram) using MART-1/Melan-A antibody

Western blot analysis of SK-MEL-3 whole cell lysate using MART-1/Melan-A antibody