Magainin 2

• Catalog Number: orb1147091
• Category: Proteins
• Description: Broad spectrum antimicrobial; Antimicrobial peptides.
• CAS Number: 108433-95-0
• Form/Appearance: Freeze dried solid
• Purity: > 95% by HPLC
• MW: 2466.9 Da
• Formula: C₁₁₄H₁₈₀N₃₀O₂₉S
• Structure: H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH
• Solubility (25°C): Soluble in dilute acid
• Protein Sequence: GIGKFLHSAKKFGKAFVGEIMNS
• Storage: Store dry, frozen and in the dark
• Alternative names: Maganin-2 , Mag-2
• Background: Magainins are closely related 23 amino acid amphipathic cationic peptides with broad-spectrum antimicrobial activities, originally extracted from the skin of the African clawed frog Xenopus laevis. Magainins 1 and magainin 2 are closely related hemolytic peptides which inhibit growth of bacteria by permeabilizing the cell membranes without significant toxicity against mammalian cells. The main target of magainin 1 and 2 is thought to be the lipid matrix of the membranes. Both magainin 1 and 2 are also cytotoxic to cancer cells and exhibit inhibitory action toward herpes simplex virus 1 and 2.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Structure for Magainin 2