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Catalog Number | orb1961965 |
---|---|
Category | Proteins |
Description | Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition, LTBR can lead to the release of the cytokine interleukin 8. |
Tag | C-6xHis |
Purity | 98.00% |
MW | 29-40 KDa (reducing condition) |
UniProt ID | P36941 |
Protein Sequence | Gln31-Met227 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition, LTBR can lead to the release of the cytokine interleukin 8. |
Expression Region | Gln31-Met227 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
98.00% | |
20.8 kDa (predicted) |
> 95% by SDS-PAGE. | |
Recombinant human LTBR/TNFRSF3 Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Gln31-Met227) of human LTBR/TNFRSF3 (Accession #NP_002333.1) fused with an Fc, 6��His Tag at the C-terminus. |