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Freight/Packing: $34.00Product Overview
Product Name | Leptin tA (PEG) protein |
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Catalog Number | orb426850 |
Conjugation | Unconjugated |
Target | Leptin tA (PEG) |
Product Properties
Form/Appearance | White lyophilized (freeze-dried) powder. The Rat Leptin triple anatagonist was lyophilized from a concentrated (0.65mg/ml) solution with 0.003mM NaHCO3. |
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Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Note | For research use only. |
Purity | >99.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE. |
Source | Escherichia coli. |
Activity | Leptin Antagonist Triple Mutant Rat Recombinant half-life in circulation after SC injection was over 20 hours.Leptin Antagonist Triple Mutant Rat Recombinant is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Leptin Antagonist Triple Mutant Rat Recombinant in vitro activity is 5-6 fold lower than the non-pegylated antagonist, though in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. |
Product Description
Recombinant of Leptin tA (PEG) protein
Solubility (25°C)
Solubility (25°C) | It is recommended to reconstitute the lyophilized Leptin Antagonist Triple Mutant Rat Recombinant in sterile water or sterile 0.4% NaHCO3adjusted to pH 8-9, not less than 100μg/ml, which can then be further diluted with other aqueous solutions. |
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