Leptin Antibody

• Catalog Number: orb1732879
• Category: Antibodies
• Description: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 8F4
• Tested applications: ELISA
• Reactivity: Human
• Isotype: Mouse IgG1
• Immunogen: Purified recombinant full length of human Leptin protein expressed in E.coli.
• Concentration: 1mg/ml
• Dilution range: ELISA: 1/10000
• Conjugation: Unconjugated
• Entrez: 3952
• UniProt ID: P41159
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: OB; OBS; LEPD; LEP
• Note: For research use only
• Expiration Date: 12 months from date of receipt.