LAMC1 antibody

• Catalog Number: orb66944
• Category: Antibodies
• Description: Rabbit polyclonal to LAMC1.Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent ofbasement membranes. They have been implicated in a wide variety of biological processes includingcell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins arecomposed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2,respectively) to form a cruciform structure consisting of 3 short arms, each by a different chain, and along arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinctgene. Several isoforms of each chain have been described. The gamma 1 chain (LAMC1) is crucialfor basement membrane formation as implicated in genetic studies with LAMC1-null mice.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: C-terminal region of human LAMC1
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 178
• UniProt ID: P11047
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-LAMC1 antibody,anti-LAMB2 antibody,anti-Lamin
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1) and mouse MEF(Lane2) using LAMC1 antibody