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Catalog Number | orb1732745 |
---|---|
Category | Antibodies |
Description | It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 7A1 |
Tested applications | ICC, IP, WB |
Reactivity | Human, Monkey |
Isotype | Mouse IgG1 |
Immunogen | Purified recombinant human Ku70 protein fragments expressed in E.coli. |
Concentration | 1mg/ml |
Dilution range | IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200 |
Conjugation | Unconjugated |
MW | Calculated MW: 70 kDa; Observed MW: 67 kDa |
Entrez | 2547 |
UniProt ID | P12956 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3. |
Alternative names | XRCC6; G22P1; X-ray repair cross-complementing pro Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, ICC, IF, IHC, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, IF, IHC, WB | |
Human | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, ICC, IF, IHC, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
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