Ku70 Antibody

• Catalog Number: orb1732622
• Category: Antibodies
• Description: It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 2F5
• Tested applications: ICC, WB
• Reactivity: Human
• Isotype: Mouse IgG2b
• Immunogen: Purified recombinant human Ku70 protein fragments expressed in E.coli.
• Concentration: 1mg/ml
• Dilution range: WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 70 kDa; Observed MW: 70 kDa
• Entrez: 2547
• UniProt ID: P12956
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: XRCC6; G22P1; X-ray repair cross-complementing pro
• Note: For research use only
• Expiration Date: 12 months from date of receipt.