Kisspeptin 10 (human)

• Catalog Number: orb1140552
• Category: Proteins
• Description: Endogenous peptide for the kisspeptin receptor KISS1 (GPR54); Peptides.
• CAS Number: 374675-21-5
• Modifications: Amide at C terminal.
• Structure: H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
• Target Areas: Kisspeptin receptors
• Form/Appearance: Freeze dried solid
• Purity: > 95% by HPLC
• MW: 1302.5 Da
• Formula: C₆₃H₈₃N₁₇O₁₄
• Solubility (25°C): Soluble in dilute acid
• Protein Sequence: H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
• Storage: Store frozen and desiccated in the dark
• Alternative names: 374675-21-5, GPR54, H-YNWNSFGLRF, H-YNWNSFGLRF-NH2
• Background: Kisspeptin 10 (human) is a potent endogenous ligand for the kisspeptin receptor (KISS1, GPR54). Kisspeptin 10 (human) binds with high affinity to rat and human KISS1 receptors, with Ki values of 1.59 and 2.33 nM respectively. Kisspeptin 10 (human) has recently emerged as a key regulator of the mammalian reproductive axis while stimulation of GPR54 can also up-regulate proapoptotic genes which have tumour suppressor properties, inhibiting metastasis and invasion in mouse melanomas.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.