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KDM7 (M) Antibody, Rabbit Polyclonal
Catalog Number: orb67002
| Catalog Number | orb67002 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to KDM7.Lysine-specific histone demethylase 7 (KDM7) is a histone demethylase required for braindevelopment. KDM7 specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 andH3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue(H4K20Me1), thereby playing a central role in histone code. KDM7 specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3,it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | IP, WB |
| Reactivity | Human |
| Immunogen | middle region of human KDM7 |
| Dilution range | WB:1:1000-1:5000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 107 |
| UniProt ID | Q6ZMT4 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-KDM7 antibody,anti-Lysinespecific demethylase Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using KDM7 antibody
