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Catalog Number | orb66993 |
---|---|
Category | Antibodies |
Description | Rabbit polyclonal to KDM5C.Lysine-specific demethylase 5C (KDM5C) is a histone demethylase that specifically demethylates'Lys-4' of histone H3, thereby playing a central role in histone code. KDM5C does not demethylatehistone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. KDM5C demethylatestrimethylated and dimethylated but not monomethylated H3 'Lys-4'. KDM5C has been shown toparticipate in transcriptional repression of neuronal genes by recruiting histone deacetylases andREST at neuron-restrictive silencer elements. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Immunogen | N-terminal region of human KDM5C |
Dilution range | WB:1:1000-1:5000 |
Purity | Affinity purification |
Conjugation | Unconjugated |
MW | 176 |
UniProt ID | P41229 |
Storage | -20°C |
Buffer/Preservatives | 0.01% NaN3 |
Alternative names | anti-KDM5C antibody,anti-Lysinespecific demethylas Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using KDM5C antibody
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