KDM5B antibody

• Catalog Number: orb66907
• Category: Antibodies
• Description: Rabbit polyclonal to KDM5B.Lysine (K)-specific demethylase 5B (KDM5B) is a ubiquitously expressed nuclear protein. It is ahistone demethylase that specifically demethylates Lys-4 of histone H3. It can demethylatetrimethylated, dimethylated, and monomethylated Lys-4. It acts as a transcriptional corepressor forFOXG1B and PAX9. It favors the proliferation of breast cancer cells by repressing tumor suppressorgenes such as BRAC1 and HOXA5. In contrast, KDM5B may act as a tumor suppressor formelanoma.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human, Mouse
• Immunogen: N-terminal region of human KDM5B
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 176
• UniProt ID: Q9UGL1
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-KDM5B antibody,anti-CT31 antibody,anti-FLJ105
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1) and mouse MEF(Lane2) using KDM5B antibody