KDM4A antibody

• Catalog Number: orb66988
• Category: Antibodies
• Description: Rabbit polyclonal to KDM4A.Lysine-specific demethylase 4A (KDM4A) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. KDM4A does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. KDM4A demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono-and dimethylated residues. KDM4A has been shown to participate in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruient of histone deacetylases and NCOR1, respectively.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: C-terminal region of human KDM4A
• Dilution range: WB:1:1000-1:5000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 121
• UniProt ID: O75164
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-KDM4A antibody,anti-Lysinespecific demethylas
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using KDM4A antibody