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Catalog Number | orb181042 |
---|---|
Category | Small Molecules |
Description | JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing > 6-fold selectivity for CDK1/2 than CDK3/4/6; also potently inhibits Aurora A/B and has no activity on Plk1 and Wee1. |
CAS Number | [443797-96-4] |
MW | 394.356 |
SMILES | S(C1C([H])=C([H])C(=C([H])C=1[H])N([H])C1N=C(N([H])[H])N(C(C2C(=C([H])C([H])=C([H])C=2F)F)=O)N=1)(N([H])[H])(=O)=O |
Formula | C15H12F2N6O3S |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
98.00% | |
443798-09-2 | |
378.43 | |
C14H14N6O3S2 |
99.66% | |
443797-96-4 | |
394.36 | |
C15H12F2N6O3S |