JHU37160

• Catalog Number: orb1089655
• Category: Small Molecules
• Description: JHU37160 is a potent and brain-penetrant DREADD agonist, with EC50s of 18.5?nM and 0.2?nM for hM3Dq and hM4Di DREADDs in HEK-293 cells, respectively. JHU37160 exhibits selective [3H]Clozapine displacement from DREADDs and not from other Clozapine-binding sites in mice brain tissue.
• CAS Number: [2369979-68-8]
• MW: 358.8403
• SMILES: ClC1C([H])=C([H])C2=C(C=1[H])N=C(C1C([H])=C([H])C([H])=C(C=1N2[H])F)N1C([H])([H])C([H])([H])N(C([H])([H])C([H])([H])[H])C([H])([H])C1([H])[H]
• Formula: C₁₉H₂₀CLFN₄
• Note: For research use only
• Expiration Date: 12 months from date of receipt.