Insulin Antibody

• Catalog Number: orb1826098
• Category: Antibodies
• Description: Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
• Clonality: Recombinant
• Species/Host: Mouse
• Isotype: Mouse IgG2a, kappa
• Conjugation: Unconjugated
• Reactivity: Human
• Immunogen: Recombinant full-length human Insulin protein was used as the immunogen for the INS antibody.
• UniProt ID: P01308
• Tested applications: IHC-P
• Dilution range: Immunohistochemistry (FFPE): 0.1-0.2ug/ml (No special pretreatment is required for staining of FFPE tissue)
• Antibody Type: Primary Antibody
• Clone Number: rIRDN/4782
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Aliquot the INS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Hazard Information: This INS antibody is available for research use only.
• Note: For research use only