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Human CLDN18.2 protein
Description
Images & Validation
−| Application Notes |
|---|
Key Properties
−| Source | Mammalian cell |
|---|---|
| Biological Origin | Homo sapiens (Human) |
| Biological Activity | Measured by its binding ability in a functional ELISA. Immobilized human CLDN18.2 at 5 μg/ml can bind anti-CLDN18.2 recombinant Monoclonal Antibody (orb783578), the the EC50 is 5.225-9.256 ng/ml |
| Tag | C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions) |
| Molecular Weight | 29.1 kDa |
| Expression Region | 1-261aa |
| Protein Length | Full Length of Isoform A2 |
| Protein Sequence | MAVTACQGLGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV |
| Endotoxins | Less than 1.0 EU/ug as determined by LAL method. |
Storage & Handling
−| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃. |
|---|---|
| Form/Appearance | Lyophilized powder |
| Buffer/Preservatives | Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4 |
| Disclaimer | For research use only |
Alternative Names
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−Human CLDN18.2 (VLP, Full Length) [orb2992808]
SEC-HPLC: Greater than 90% as determined by SEC-HPLC.(QC verified)
Predicted: 28.7 KDa
100 μg, 20 μgHuman CLDN18.2 full length protein-synthetic nanodisc [orb1291760]
The human full length CLDN18.2 Protein has a MW of 27.5 kDa
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50 μg, 100 μg, 10 μgHuman CLDN18.2 full length protein-VLP [orb1291767]
The Human Claudin 18.2 Protein has a predicted MW of 29 kDa.Due to PTM, the actual MW on SDS-PAGE gel is around 50kDa.
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50 μg, 100 μgFluorescent Human CLDN18.2 Full Length Protein-VLP (EGFP) [orb1471702]
The human full length CLDN18.2 fusion protein has a MW of 54.2 kDa
Mammalian
25 T, 100 TCynomolgus CLDN18.2 Protein, hFc Tag [orb2321264]
The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 31.9 kDa after removal of the signal peptide.
Mammalian
10 μg, 50 μg, 100 μg

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Western Blot is detected by Mouse anti-6*His monoclonal antibody.The three bands respectively correspond to monomer, Homodimer, Homotrimer

Measured by its binding ability in a functional ELISA. Immobilized human CLDN18.2 at 5 μg/ml can bind anti-CLDN18.2 recombinant Monoclonal Antibody, the the EC50 is 5.225-9.256 ng/ml.

The presence of VLP-like structures was confirmed by TEM

Western Blot is detected by Anti-Claudin 18 Antibody.The two bands respectively correspond to monomer, Homodimer
Quick Database Links
UniProt Details
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Protocol Information
Human CLDN18.2 protein (orb865262)
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