IL17A Rabbit Polyclonal Antibody

• Catalog Number: orb10898
• Category: Antibodies
• Description: IL17A Rabbit Polyclonal Antibody
• Target: IL17A
• Clonality: Polyclonal
• Species/Host: Rabbit
• Isotype: IgG
• Conjugation: Unconjugated
• Reactivity: Mouse, Rat
• Predicted Reactivity: Rat
• Form/Appearance: Liquid
• Concentration: 1mg/ml
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Purification: Affinity purified by Protein A
• Immunogen: KLH conjugated synthetic peptide derived from mouse IL-17 (85-150/150aa)
• UniProt ID: Q62386
• RRID: AB_10750558
• MW: 15-17 kDa
• Tested applications: IF, IHC-Fr, IHC-P, WB
• Dilution range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Antibody Type: Primary Antibody
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: Interleukin-17A; CTLA-8; CTLA 8; CTLA8; Cytotoxic
• Research Area: Cell Biology, Interleukins
• Note: For research use only

References

Ayantika Kundu 1, Pratiti Ghosh 2, Biswadev Bishayi Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3 Int Immunopharmacol, (2024)

PubMed: 38678669

Applications

WB

Reactivity

Mouse

Rituparna Ghosh 1, Biswadev Bishayi Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes Cell Immunol, (2024)

PubMed: 39312873

Applications

WB

Reactivity

Mouse

Rituparna Ghosh 1, Biswadev Bishayi Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages Microb Pathog, (2024)

PubMed: 38160988

Applications

WB

Reactivity

Mouse

Sample: Lane 1: Rat Lymph node tissue lysates, Lane 2: Mouse Lymph node tissue lysates, Lane 3: Rat Thymus tissue lysates, Primary: Anti-IL17A (orb10898) at 1/1000 dilution, Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution, Predicted band size: 15 kD, Observed band size: 22 kD.