IL17A Rabbit Polyclonal Antibody

SKU: orb10898

Description

IL17A Rabbit Polyclonal Antibody

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Mouse, Rat
• Predicted Reactivity: Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated synthetic peptide derived from mouse IL-17 (85-150/150aa)
• Target: IL17A
• Molecular Weight: 22 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CTLA-8; CTLA8; IL-17; IL-17A; IL17; ILA17; IL17_HUMAN; IL17A; Cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8); IL17_MOUSE; IL17_RAT; interleukin 17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); cytotoxic T-lymphocyte-associated protein 8

Quick Database Links

Gene Symbol

IL17A

UniProt

Q62386

Ayantika Kundu 1, Pratiti Ghosh 2, Biswadev Bishayi Verapamil and tangeretin enhances the M1 macrophages to M2 type in lipopolysaccharide-treated mice and inhibits the P-glycoprotein expression by downregulating STAT1/STAT3 and upregulating SOCS3 Int Immunopharmacol, (2024)

PubMed: 38678669

Applications

WB

Reactivity

Mouse

Rituparna Ghosh 1, Biswadev Bishayi Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes Cell Immunol, (2024)

PubMed: 39312873

Applications

WB

Reactivity

Mouse

Rituparna Ghosh 1, Biswadev Bishayi Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages Microb Pathog, (2024)

PubMed: 38160988

Applications

WB

Reactivity

Mouse