IL-29 Protein, Human, Recombinant (His)

Catalog Number: orb1957707

Catalog Number	orb1957707
Category	Small Molecules
Description	IL-29 Protein, Human, Recombinant (His)
Purity	98.00%
MW	Approxiamtely 21.4 kDa
Biological Activity	Interleukin-29 (IL-29), also known as cytokine Zcyto21, Interferon lambda-1, IFN-lambda-1, and IFNL1, is a secreted protein that belongs to the IL-28 / IL-29 family. IL-29 is a cytokine with immunomodulatory activity. IL-29 is highly similar in amino acid sequence to the IL-28. IL-28 and IL-29 are induced by a viral infection and showed antiviral activity. IL-28 and IL-29 interacted with a heterodimeric class II cytokine receptor that consisted of IL-10 receptor beta (IL-10Rbeta) and an orphan class II receptor chain, designated IL-28Ralpha. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses. IL-29 may play a role in antiviral immunity. IL-29 up-regulates MHC class I antigen expression. It is a Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
Note	For research use only
Expiration Date	12 months from date of receipt.

Purity:	> 95% by SDS-PAGE.
Source:	KMP1401, Recombinant Human IL-29 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Gly20-Thr200) of human IL-29 (Accession #NP_742152.1) fused with a 6×His Tag at the C-terminus.

Sizes Available: 100 μg, 50 μg

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human IFNL1(Met1-Thr200) was fused with the C-terminal His Tag and expressed in Mammalian cells.