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Catalog Number | orb2636494 |
---|---|
Category | Antibodies |
Description | Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | IL2/9007 |
Tested applications | IHC-P |
Reactivity | Human |
Isotype | Mouse IgG2a, kappa |
Immunogen | A recombinant fragment (within amino acids 1-153) of human IL2 protein was used as the immunogen for the IL-2 antibody. |
Antibody Type | Primary Antibody |
Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml |
Conjugation | Unconjugated |
Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
Hazard Information | This IL-2 antibody is available for research use only. |
UniProt ID | P60568 |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Note | For research use only |
Application notes | Optimal dilution of the IL-2 antibody should be determined by the researcher. |
Expiration Date | 12 months from date of receipt. |
IHC staining of FFPE human adrenal gland tissue with IL-2 antibody (clone IL2/9007). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free IL-2 antibody (clone IL2/9007) as confirmation of integrity and purity.
ELISA, FACS, IF, IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
ELISA, FACS, IF, IHC-P, WB | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
Blocking, FC, IF, IHC, WB | |
Human, Primate | |
Human | |
Monoclonal | |
Unconjugated |
Blocking, FC, IF, IHC, WB | |
Human, Primate | |
Human | |
Monoclonal | |
Unconjugated |
Blocking, FC, IF, IHC, WB | |
Human, Primate | |
Human | |
Monoclonal | |
Unconjugated |