IL-17A antibody

• Catalog Number: orb758854
• Category: Antibodies
• Description: Rabbit monoclonal antibody to IL-17A
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: MM17F3
• Tested applications: Blocking, ELISA
• Reactivity: Mouse
• Isotype: IgG
• Immunogen: This antibody was raised by immunising C57Bl/6 mice with IL-17A cross-linked to ovalbumin to generate a highly immunogenic complex.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: IL-17A
• UniProt ID: Q62386
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Interleukin-17A; IL17A; Cytotoxic T-lymphocyte-ass
• Note: For research use only
• Application notes: The specificity of this antibody has been confirmed in ELISA analysis (Uyttenhove et al, 2006). This antibody inhibits IL‐17A‐induced IL‐6 production by a Cl1D fibroblastic cell line in vitro (Uyttenhove et al, 2006). This antibody has been shown to prevent experimental autoimmune encephalomyelitis (EAE) disease development in vivo (Uyttenhove et al, 2006), as well as protecting C57Bl/6 mice from myelin oligdendrocyte glycoprotein (MOG)-induced EAE (Uyttenhove et al, 2007). Additionally, administration of this antibody inhibits collagen-induced arthritis (CIA) in IFN-γ receptor knockout mice (Kelchtermans et al, 2009).
• Expiration Date: 12 months from date of receipt.