IDO 2 Antibody

• Catalog Number: orb1729917
• Category: Antibodies
• Description: INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small inTine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, WB
• Reactivity: Human
• Isotype: Rabbit IgG
• Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IDO2. AA range:101-150
• Dilution range: WB: 1/500-1/1000; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: Calculated MW: 47 kDa; Observed MW: 47 kDa
• Entrez: 169355
• UniProt ID: Q6ZQW0
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: IDO2; INDOL1; Indoleamine 2; 3-dioxygenase 2; IDO-
• Note: For research use only
• Expiration Date: 12 months from date of receipt.