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Catalog Number | orb1089588 |
---|---|
Category | Small Molecules |
Description | ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1). ICCB-19 effectively induces autophagy. |
CAS Number | [1803605-68-6] |
MW | 291.840580463409 |
SMILES | Cl.C1(NC(=O)CSC2NCCN=2)CCCCCC1 |
Formula | C12H22CLN3OS |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
99.30% | |
1803605-68-6 | |
291.84 | |
C12H22ClN3OS |