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Catalog Number | orb216651 |
---|---|
Category | Proteins |
Description | Humanin Human peptide |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
Protein Sequence | Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala |
MW | 2687.23 |
Application notes | Humanin (HN) is a polypeptide suppressing neuronal cell death induced by several familial Alzheimer's disease genes and by amyloid β-protein (1-43) (human). It has been shown that amyloid β-protein (1-40) and amyloid β-protein (1-42) secretion is not affected by humanin in F11 cells expressing the familial Alzheimer's disease gene K595N/M596L-APP. Inhibitory actions on neuronal cell death triggered by K595N/M596L-APP directly and caused by amyloid β-protein have been suggested. |
Source | Synthetic |
CAS Number | 330936-69-1 |
Formula | C121H205F3N34O34S2 |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Note | For research use only |
Human | |
28 pg/mL-1800 pg/mL | |
7 pg/mL |
Human | |
31.25-2000 pg/mL | |
12.3 pg/mL |