Human RACK1 protein

SKU: orb754920

Description

Recombinant human RACK1 protein

Research Area

Apoptotic, Cancer, Developmental Biology, Epigenetics, Infectious Diseases, Neuroscience, Signaling Pathways

Images & Validation

• Tested Applications: ELISA, WB
• Application Notes:
  Centrifuge the vial at 10,000 rpm for 1 minute, reconstitute at 200 μg/ml in sterile distilled water by gentle pipetting 2-3 times, don’t vortex

Key Properties

• Source: E.Coli
• Reactivity: Human
• Tag: N-terminal His Tag
• Molecular Weight: 34.8 kDa
• Expression Region: 1-317
• Purity: Greater than 95% as determined by SDS-PAGE

Storage & Handling

• Storage: -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered solution in 10 mM Hepes, 500 mM NaCl with 5% trehalose, pH 7.4
• Disclaimer: For research use only

Alternative Names

Cell proliferation-inducing gene 21 protein, GBLP_HUMAN, Gnb2-rs1, Gnb2l1, Guanine nucleotide binding protein (G protein) beta polypeptide 2 like 1, Guanine nucleotide binding protein beta polypeptide 2 like 1, Guanine nucleotide binding protein beta subunit 2 like 1, Guanine nucleotide binding protein beta subunit like protein 12.3, Guanine nucleotide binding protein subunit beta 2 like 1

Quick Database Links

UniProt

P63244

References

Jian Cui 1, Meng Yang 1, Chengli Yu 1, Haidong Zhang 2, Yuan Gong 1, Yang Hu 1, Yue Wang 1, Qingxin Yuan 1, An Pan 1, Jiepin Li 2, Yaowen Hu 1, Zecheng Jin 1, Xuemei Peng 1, Anyuan Wu 1, Junwei Wang 1, Qian Wang 2, Yinan Zhang 1, Lihong Hu Inhibition of RACK1-Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome Adv Sci (Weinh) ., (2025)

PubMed: 40349158

Applications

SBR

Y Zhang, J Cui, M Yang, C Yu, H Zhang, Y Gong, Y Hu, Y Wang, Q Yuan, A Pan, J Li, Y Hu… Inhibition of NLRP3 oligomerization (active conformation) mediated by RACK1 ameliorates acute respiratory distress syndrome researchsquare.com, (2024)

PubMed:

Applications

SPR