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Human PSCA Protein
Catalog Number: orb636720
| Catalog Number | orb636720 |
|---|---|
| Category | Proteins |
| Description | The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs. |
| Reactivity | Human |
| Tag | C-10×His |
| Form/Appearance | Powder |
| Purity | 90% |
| Conjugation | Unconjugated |
| MW | 10.4 kDa |
| Target | PSCA |
| Protein Sequence | NP_005663.2 |
| Source | Human PSCA, His Tag (orb636720) is expressed from human 293 cells (HEK293). It contains AA Leu 12 - Ser 86 (Accession # O43653-1). |
| Expression System | HEK293 |
| Expression Region | Leu 12 - Ser 86 |
| Endotoxins | 1.0 EU per μg |
| NCBI | NP_005663.2 |
| Storage | -20℃ |
| Buffer/Preservatives | PBS, pH7.4 |
| Alternative names | PSCA,UNQ206,PRO232 Read more... |
| Note | For research use only |
| Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.4 kDa. The protein migrates as 18-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
Human PSCA protein [orb704587]
Greater than 90% as determined by SDS-PAGE.
13.4 kDa
E.coli
20 μg, 100 μg, 1 mgHuman PSCA protein [orb54171]
Greater than 90% as determined by SDS-PAGE.
9.7 kDa
Yeast
20 μg, 100 μg, 500 μg, 1 mgHuman PSCA protein [orb244466]
Greater than 90% as determined by SDS-PAGE.
35.7kDa
E.coli
20 μg, 100 μg, 1 mgHuman PSCA Protein, hFc Tag [orb689427]
Unconjugated
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide.The apparent molecular mass of PSCA-hFc is approximately 40-57 kDa due to glycosylation.
Mammalian
10 μg, 50 μg, 100 μgHuman PSCA Protein [orb1477776]
Greater than 85% as determined by SDS-PAGE.
14.2 kDa
E.coli
20 μg, 100 μg, 1 mg
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