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Catalog Number | orb1184791 |
---|---|
Category | Proteins |
Description | Podoplanin (PDPN) is a type I transmembrane mucin-like glycoprotein expressed in the lymphatic endothelium. It is overexpressed in several solid tumors, such as squamous cell carcinoma, malignant mesothelioma, Kaposi sarcoma, angiosarcoma, testicular seminoma, and brain tumors. PDPN expression is associated with malignant progression, epithelial–mesenchymal transition, and metastasis. |
Reactivity | Human |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 90% |
Conjugation | Unconjugated |
MW | 37.6 kDa |
Target | Podoplanin |
Protein Sequence | NP_006465.3 |
Source | Human Podoplanin, Fc Tag (orb1184791) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Leu 131 (Accession # Q86YL7-1). |
Expression System | HEK293 |
Expression Region | Ala 23 - Leu 131 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_006465.3 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | Podoplanin,PDPN,Gp36 Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 37.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Unconjugated | |
90% | |
13.0 kDa | |
Human Podoplanin, His Tag (orb1184794) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Leu 131 (Accession # Q86YL7-1). |
≥90% as determined by SDS-PAGE | |
This protein contains the human PDPN(Ala23-Leu131) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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