Human Podoplanin / PDPN Protein, His Tag

Catalog Number: orb1184794

Catalog Number	orb1184794
Category	Proteins
Description	Podoplanin (PDPN) is a type I transmembrane mucin-like glycoprotein expressed in the lymphatic endothelium. It is overexpressed in several solid tumors, such as squamous cell carcinoma, malignant mesothelioma, Kaposi sarcoma, angiosarcoma, testicular seminoma, and brain tumors. PDPN expression is associated with malignant progression, epithelial–mesenchymal transition, and metastasis.
Reactivity	Human
Tag	C-10×His
Form/Appearance	Powder
Purity	90%
Conjugation	Unconjugated
MW	13.0 kDa
Target	Podoplanin
Protein Sequence	NP_006465.3
Source	Human Podoplanin, His Tag (orb1184794) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Leu 131 (Accession # Q86YL7-1).
Expression System	HEK293
Expression Region	Ala 23 - Leu 131
Endotoxins	1.0 EU per μg
NCBI	NP_006465.3
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	Podoplanin,PDPN,Gp36 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.0 kDa. The protein migrates as 19-21 kDa and 30-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human PDPN(Ala23-Leu131) was fused with the C-terminal His Tag and expressed in Mammalian cells.