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Human MANF protein
Catalog Number: orb107776
| Catalog Number | orb107776 |
|---|---|
| Category | Proteins |
| Description | Mesencephalic astrocyte-derived neurotrophic factor, also known as Protein ARMET, Arginine-rich protein, MANF andARMET, is a secreted protein which belongs to the ARMET family. Recombinant human MANF produced by E. coli is a singlepolypeptide chain containing 183 amino acids (25-182) and having a molecular mass of 20.8kDa. MANF reduces endoplasmicreticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. MANF has been described as a survival factor fordopaminergic neurons. MANF expression was widespread in the nervous system and non-neuronal tissues. Mature humanMANF is 99%, 98% and 96% a.a. identical to mature rat, mouse and bovine MANF respectively |
| Target | MANF |
| Conjugation | Unconjugated |
| Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
| Purity | > 95% by SDS-PAGE and HPLC analyses. |
| Protein Sequence | LRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDAATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKILDDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL |
| MW | 18.2 kDa |
| Tested applications | HPLC, SDS-PAGE |
| Biological Origin | E.coli |
| Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
| Alternative names | Human Mesencephalic Astrocyte-Derived Neurotrophic Read more... |
| Note | For research use only |
SDS-PAGE analysis of Human MANF protein
- Item 1 of 1
Human MANF protein (Active) [orb359281]
> 95% as determined by SDS-PAGE and HPLC.
18.2 kDa
E.Coli
100 μg, 500 μg, 5 μg 
Human MANF protein [orb392116]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
Human cells
10 μg, 50 μg, 500 μg- Item 1 of 1
- Item 1 of 1
