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Catalog Number | orb348820 |
---|---|
Category | Proteins |
Description | Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. |
Reactivity | Human |
Tag | N-6×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 36.6 kDa |
Target | Galectin-9 |
Protein Sequence | BAA31542.1 |
Source | Human Galectin-9, His Tag (orb348820) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2). |
Expression System | HEK293 |
Expression Region | Ala 2 - Thr 323 |
Endotoxins | 1.0 EU per μg |
NCBI | BAA31542.1 |
Storage | -20℃ |
Buffer/Preservatives | 20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4 |
Alternative names | Galectin-9,LGALS9,Ecalectin Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE). |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human Galectin-9 protein
> 95% by SDS-PAGE. | |
KMP1718, Recombinant Human Galectin-9/LGALS9 Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Met1-Thr323) of human Galectin-9/LGALS9 (Accession #Q3B8N1-2) fused with a 6×His Tag at the C-terminus. |
≥90% as determined by SDS-PAGE | |
This protein contains the human LGALS9(Ala2-Thr323)was fused with the N-terminal Fc Tag and expressed in Mammalian cells. |
≥90% as determined by SDS-PAGE | |
This protein contains the human LGALS9(Met1-Gln148) was fused with the N-terminal His Tag and expressed in E. coli. |
Biotin | |
90% | |
39.3 kDa | |
Biotinylated Human Galectin-9, His, is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2). |
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