Biotinylated Human Galectin-9 / LGALS9 Protein, His, (SPR verified)

• Catalog Number: orb1806470
• Category: Proteins
• Description: Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
• Reactivity: Human
• Tag: N-10×His & N-Avi
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Biotin
• MW: 39.3 kDa
• Target: Galectin-9
• Source: Biotinylated Human Galectin-9, His, is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2).
• Expression System: HEK293
• Expression Region: Ala 2 - Thr 323
• Endotoxins: 1.0 EU per μg
• Storage: -20°C
• Buffer/Preservatives: 20 mM MOPS, 50 mM Nacl, 1 mM EDTA, 2 mM DTT, pH 7.4
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (). The protein has a calculated MW of 39.3 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.