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Human FGF acidic Protein
Catalog Number: orb257176
| Catalog Number | orb257176 |
|---|---|
| Category | Proteins |
| Description | Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways. |
| Reactivity | Human |
| Tag | Native |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 16.0 kDa |
| Target | FGF acidic |
| Protein Sequence | NP_000791.1 |
| Source | Human FGF acidic, Tag Free (orb257176) is expressed from E. coli cells. It contains AA Phe 16 - Asp 155 (Accession # P05230-1). |
| Expression System | E. coli |
| Expression Region | Phe 16 - Asp 155 |
| Endotoxins | 1.0 EU per μg |
| NCBI | NP_000791.1 |
| Storage | -20℃ |
| Buffer/Preservatives | PBS, pH7.4 |
| Alternative names | FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGF Read more... |
| Note | For research use only |
| Application notes | This protein carries no "tag". The protein has a calculated MW of 16.0 kDa. The protein migrates as 16 kDa under reducing (R) condition (SDS-PAGE). |
| Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human FGF acidic protein
- Item 1 of 2
Human FGF basic Protein [orb257225]
Unconjugated
95%
16.5 kDa
Human FGF basic, premium grade (orb257225) is expressed from E. coli cells. It contains AA Pro 143 - Ser 288 (Accession # P09038-4).
20 μg, 1 mg, 50 μg 
Human FGF1 protein [orb604089]
Greater than 85% as determined by SDS-PAGE.
17.8 kDa
E.coli
20 μg, 100 μg, 1 mgHuman FGF1 protein [orb391720]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgHuman FGF1 protein [orb391721]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgHuman FIBP protein [orb391742]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μg
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