Human Fetuin B Protein

• Catalog Number: orb257468
• Category: Proteins
• Description: Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 42.4 kDa
• Target: Fetuin B
• Protein Sequence: AAH69670
• Source: Human Fetuin B, His Tag (orb257468) is expressed from human 293 cells (HEK293). It contains AA Cys 16 - Pro 382 (Accession # AAH69670 ).
• Expression System: HEK293
• Expression Region: Cys 16 - Pro 382
• Endotoxins: 1.0 EU per μg
• NCBI: AAH69670
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, 150 mM NaCl, pH8.0
• Alternative names: FETUB,Fetuin-B,16G2,Gugu
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.4 kDa. The protein migrates as 53-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Fetuin B protein