You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb257416 |
---|---|
Category | Proteins |
Description | The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. |
Reactivity | Human |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 94.7 kDa |
Target | EGF R |
Protein Sequence | NP_005219 |
Source | Human EGF R, Fc Tag (orb257416) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1). |
Expression System | HEK293 |
Expression Region | Leu 25 - Ser 645 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_005219 |
Storage | -20°C |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | EGFR,ERBB,ERBB1,HER1,PIG61,mENA Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 94.7 kDa. The protein migrates as 110-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human EGF R protein
Unconjugated | |
95% | |
70.5 kDa | |
Human EGF R, His Tag (orb257415) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1). |
> 97% as determined by SDS-PAGE and HPLC. | |
9.7 kDa | |
E.Coli |
Greater than 85% as determined by SDS-PAGE. | |
11.7 kDa | |
Yeast |
Human | |
0.312 ng/mL-20 ng/mL | |
0.019 ng/mL |
Human | |
0.16-10ng/mL | |
0.1 ng/mL |
Filter by Rating