Human Decorin Protein

• Catalog Number: orb257393
• Category: Proteins
• Description: Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 38.8 kDa
• Target: Decorin
• Protein Sequence: NP_001911.1
• Source: Human Decorin, His Tag (orb257393) is expressed from human 293 cells (HEK293). It contains AA Gly 17 - Lys 359 (Accession # NP_001911.1).
• Expression System: HEK293
• Expression Region: Gly 17 - Lys 359
• Endotoxins: 1.0 EU per μg
• NCBI: NP_001911.1
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: Decorin,DCN,CSCD,DSPG2,PG40,PGII,PGS2,SLRR1B
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.8 kDa. The protein migrates as 46-55 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Decorin protein