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Catalog Number | orb257353 |
---|---|
Category | Proteins |
Description | Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage. |
Reactivity | Human |
Tag | C-11×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 37.6 kDa |
Target | CNTF R alpha |
Protein Sequence | AAH01492 |
Source | Human CNTF R alpha, His Tag (orb257353) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Pro 346 (Accession # AAH01492). |
Expression System | HEK293 |
Expression Region | Gln 23 - Pro 346 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH01492 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | CNTFR,CNTF R alpha Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human CNTF R alpha protein
Unconjugated | |
95% | |
39.6 kDa | |
Human IL-11 R alpha, His Tag (orb1149284) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Ala 370 (Accession # Q14626-1). |
> 95% by SDS-PAGE. | |
KMP1553, Recombinant Human CNTF R alpha Protein is produced by HEK293 Cells expression system. The target protein is expressed with sequence (Gln 23 - Pro 346 ) of human CNTF R alpha (Accession #NP_001833.1) fused with a 6×His Tag at the C-terminus. |
Unconjugated | |
95% | |
69.6 kDa | |
Human gp130, His Tag (orb1496208) is expressed from human 293 cells (HEK293). It contains AA Glu 23 - Glu 619 (Accession # P40189-1). |
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