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Human CD44 Protein
Catalog Number: orb257773
| Catalog Number | orb257773 |
|---|---|
| Category | Proteins |
| Description | CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms. |
| Reactivity | Human |
| Tag | C-Fc |
| Form/Appearance | Powder |
| Purity | 95% |
| Conjugation | Unconjugated |
| MW | 48.7 kDa |
| Target | CD44 |
| Protein Sequence | AAH04372 |
| Source | Human CD44 Protein, Fc Tag (orb257773) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Pro 220 (Accession # AAH04372). |
| Expression System | HEK293 |
| Expression Region | Gln 21 - Pro 220 |
| Endotoxins | 1.0 EU per μg |
| NCBI | AAH04372 |
| Storage | -20℃ |
| Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
| Alternative names | CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC5 Read more... |
| Note | For research use only |
| Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.7 kDa. The protein migrates as 55-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human CD44 protein
- Item 1 of 2
Human CD44 Protein [orb257269]
Unconjugated
90%
23.3 kDa
Human CD44, His Tag (orb257269) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Pro 220 (Accession # AAH04372).
1 mg, 100 μg 
Human CD44 protein [orb704579]
Greater than 85% as determined by SDS-PAGE.
38.1 kDa
E.coli
20 μg, 100 μg, 1 mgHuman CD44 protein [orb704580]
Greater than 85% as determined by SDS-PAGE.
43.6 kDa
E.coli
20 μg, 100 μg, 1 mgHuman CD44 protein [orb244086]
Greater than 90% as determined by SDS-PAGE.
80.2 kDa
E.coli
20 μg, 100 μg, 1 mgHuman CD44 Protein, His Tag [orb757431]
Unconjugated
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 22.9 kDa after removal of the signal peptide.The apparent molecular mass of CD44-His is approximately 35-55 kDa due to glycosylation.
Mammalian
100 μg, 10 μg, 50 μg
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