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Catalog Number | orb257733 |
---|---|
Category | Proteins |
Description | CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion. |
Reactivity | Human |
Tag | C-Fc |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 48.6 kDa |
Target | CD200 |
Protein Sequence | AAH22522 |
Source | Human CD200, Fc Tag (orb257733) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gly 232 (Accession # AAH22522). |
Expression System | HEK293 |
Expression Region | Gln 31 - Gly 232 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH22522 |
Storage | -20℃ |
Buffer/Preservatives | 50 mM Tris, 100 mM Glycine, pH7.5 |
Alternative names | CD200,MOX1,MOX2,MRC,OX-2,My033 Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 55-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human CD200 protein
Unconjugated | |
98% | |
23.3 kDa | |
Human CD200, His Tag (orb257732) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gly 232 (Accession # AAH22522). |
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