Human CD200 / OX-2 Protein

• Catalog Number: orb257732
• Category: Proteins
• Description: CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 98%
• Conjugation: Unconjugated
• MW: 23.3 kDa
• Target: CD200
• Protein Sequence: AAH22522
• Source: Human CD200, His Tag (orb257732) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gly 232 (Accession # AAH22522).
• Expression System: HEK293
• Expression Region: Gln 31 - Gly 232
• Endotoxins: 1.0 EU per μg
• NCBI: AAH22522
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: CD200,MOX1,MOX2,MRC,OX-2,My033
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.3 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human CD200 protein