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Catalog Number | orb257210 |
---|---|
Category | Proteins |
Description | Human BACE-1, Tag Free is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1). |
Reactivity | Human |
Tag | Native |
Form/Appearance | Powder |
Purity | 98% |
Conjugation | Unconjugated |
MW | 49.0 kDa |
Target | BACE-1 |
UniProt ID | P56817 |
Protein Sequence | NP_036236.1 |
Source | Human BACE-1, Tag Free (orb257210) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1). |
Expression System | HEK293 |
Biological Origin | Human |
Expression Region | Thr 22 - Thr 457 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_036236.1 |
Storage | -20℃ |
Buffer/Preservatives | 50 mM Tris, pH8.0 |
Alternative names | BACE1,ASP2,BACE,FLJ90568,HSPC104,KIAA1149,Memapsin Read more... |
Note | For research use only |
Application notes | This protein carries no "tag". The protein has a calculated MW of 49.0 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Peters-Libeu, Clare et al. sAβPPα is a Potent Endogenous Inhibitor of BACE1 J Alzheimers Dis, 47, 545-555 (2015)
SDS-PAGE analysis of Human BACE-1 protein
Unconjugated | |
95% | |
49.3 kDa | |
Human BACE-1, His Tag (orb257211) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1). |
Unconjugated | |
90% | |
75.2 kDa & 72.6 kDa | |
Human BACE-1, Fc Tag (orb257212) is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1). |
98.00% | |
120-145 KDa (reducing condition) |
ELISA, WB | |
Greater than 95% by SDS-PAGE gel analyses | |
32.5 KDa | |
E.Coli |
ELISA, WB | |
Greater than 95% by SDS-PAGE gel analyses | |
32.5 KDa | |
E.Coli |