Cart summary

You have no items in your shopping cart.

Human B7-H4 Protein

Human B7-H4 Protein

Catalog Number: orb511239

DispatchUsually dispatched within 5-10 working days
$ 3,885.00
Catalog Numberorb511239
CategoryProteins
DescriptionV-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1 / B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.
ReactivityHuman
TagC-Fc
Form/AppearancePowder
Purity95%
ConjugationUnconjugated
MW51.8 kDa
TargetB7-H4
Protein SequenceNP_078902.2
SourceHuman B7-H4 Protein, Fc Tag (orb511239) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # Q7Z7D3-1).
Expression SystemHEK293
Expression RegionPhe 29 - Ala 258
Endotoxins0.01 EU per μg
NCBINP_078902.2
Storage-20℃
Buffer/PreservativesPBS, pH7.4
Alternative namesB7-H4,VTCN1,B7S1,B7h.5
Read more...
NoteFor research use only
Application notesThis protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.8 kDa. The protein migrates as 66-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date6 months from date of receipt.
  • Human B7-H4 Protein [orb257208]

    Unconjugated

    90%

    26.4 kDa

    Human B7-H4, His Tag (orb257208) is expressed from human 293 cells (HEK293). It contains AA Phe 29 - Ala 258 (Accession # NP_078902).

    1 mg, 100 μg
  • Human VTCN1 ELISA Kit [orb777385]

    Human

    0.16-10 ng/mL

    0.058 ng/mL

    96 Test, 48 Test, 24 t
  • Human VTCN1 ELISA Kit [orb562606]

    Human

    7.8-500ng/ml

    4.688ng/ml

    96 Test
  • Human B7-H4 Protein, hFc Tag [orb757460]

    Unconjugated

    The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 51.4 kDa after removal of the signal peptide.The apparent molecular mass of B7-H4-hFc is approximately 100-130 kDa due to glycosylation.

    Mammalian

    50 μg, 100 μg, 10 μg
  • Human VTCN1 ELISA Kit [orb405641]

    Human

    7.8 ng/mL-500 ng/mL

    1.95 ng/mL

    10 x 96 t, 5 x 96 t, 96 t, 48 t, 24T
Submit a review

Filter by Rating

    • Star
    • Star
    • Star
    • Star
    • Star
    • 5 stars
    • Star
    • Star
    • Star
    • Star
    • Star
    • 4 stars
    • Star
    • Star
    • Star
    • Star
    • Star
    • 3 stars
    • Star
    • Star
    • Star
    • Star
    • Star
    • 2 stars
    • Star
    • Star
    • Star
    • Star
    • Star
    • 1 stars