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Catalog Number | orb216646 |
---|---|
Category | Proteins |
Description | Histatin 5 peptide |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
Protein Sequence | H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH |
MW | 3036.36 |
Application notes | Histatin-5, a salivary polypeptide, has been shown to inhibit clostripain (IC₅₀ = 800 nM) and a trypsin-like protease produced by Bacteroides gingivalis (IC₅₀ = 55 nM). Other proteases, however, have not been inhibited by histatin-5. This peptide was therefore suggested to be a preventive against periodontal disease. Histatin-5 exhibits antimicrobial and a distinct antifungal activity targetting fungal mitochondria. |
Source | Synthetic |
CAS Number | 104339-66-4 |
Formula | C133H195N51O33 |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 95% by HPLC | |
3036.3 Da | |
H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-OH |