HFE2 Antibody (C-term)

SKU: orb40399

Description

Rabbit polyclonal antibody to HFE2 also known as Hemojuvelin, is a membrane-bound and soluble protein which belongs to the repulsive guidance molecule (RGM) family. It may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. This gene is involved in iron metabolism.

Research Area

Metabolism Research, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

• Tested Applications: FC, WB
• Dilution Range: WB - 1:1000, FC - 1:10-50
• Reactivity: Human
• Predicted Reactivity: Mouse, Rat

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Clone No.: BTD44308
• Immunogen: Synthetic Peptide
• Target: HJV
• Molecular Weight: 45080
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Form/Appearance: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Anti-RGM domain family member C antibody, anti-Hemochromatosis type 2 protein antibody, anti-Hemojuvelin, RGMC antibody, anti-HJV antibody, anti-HFE2 antibody

Western blot analysis of HFE2 Antibody (C-term) in HepG2 cell line lysates (35 ug/lane). HFE2 (arrow) was detected using the purified Pab.

HFE2 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Quick Database Links

Gene Symbol

HJV

UniProt

Q6ZVN8

RefSeq (Protein):NP_998818.1, NP_998817.1, NP_660320.3, NP_973733.1