HAKAI (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb67187
• Category: Antibodies
• Description: Rabbit polyclonal to HAKAI.HAKAI is also known as Casitas B-lineage lymphoma-transforming sequence-like protein 1 (CBLL1),which is an E3 ubiquitin-protein ligase for the E-cadherin (CDH1) complex and mediates itsubiquitination, endocytosis, and degradation in the lysosomes. CDH1 is endocytosed as aconsequence of tyrosine phosphorylation and ubiquitination. HAKAI interacts with tyrosinephosphorylatedCDH1 and mediates this process. HAKAI contains a RING-finger domain and is alsothought to have a role in the control of cell proliferation.
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of human HAKAI
• UniProt ID: Q75N03
• MW: 54.5
• Tested applications: WB
• Dilution range: WB:1:500-1:1000
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: anti-HAKAI antibody,anti-E3 ubiquitinprotein ligas
• Research Area: Developmental Biology, Epigenetics
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela using HAKAI antibody