HA antibody

• Catalog Number: orb1463359
• Category: Antibodies
• Description: Human monoclonal antibody to HA
• Species/Host: Human
• Clonality: Monoclonal
• Clone Number: CR6261
• Reactivity: Virus
• Isotype: IgG1
• Immunogen: The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: HA
• UniProt ID: Q9WFX3
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Hemagglutinin; Avian Influenza Virus; AIV; H1N1; H
• Note: For research use only
• Application notes: The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576).
• Expiration Date: 12 months from date of receipt.